Well, if you talk to the head of Security enough he’ll open a quest line to kill the ghoul and his friends for some caps and a Chinese Assault Rifle (or Assault Rifle, it scales with level). But if you then talk to the ghoul you’ll get the option to release a horde of ferals on the tower and murder everyone inside.
That….or you convince everyone in the tower to live with the ghouls. Apparently you return later and they’re all dead save for the ghouls, with the ghouls citing that they had a disagreement with the previous tenants.
That sounds like the most morally gray of the options, but I *edited*ed a few people off by calling them bigots so they won’t agree with me and when I killed Tenpenny (Good karma for that!) the head of security takes over and refuses. So, it’s either murder the ghouls or murder the tenants. I.E. Take the Caps or Get the Mask, but suffer through karma along the way.